Synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the natural pineal peptide epithalamin, developed by Vladimir Khavinson. Epithalon activates telomerase (hTERT) to maintain telomere length, modulates melatonin synthesis via pinealocyte regulation, and has demonstrated lifespan extension in multiple animal models.
Research FocusTelomere maintenance, melatonin modulation, aging biology, lifespan studies
ReconstitutionBacteriostatic water — 5 mg/mL
Stability21 days at 2–8°C
Key distinction: The only commercially available peptide with direct telomerase activation evidence — addresses the telomere shortening hallmark of aging at the chromosomal level.
Scientific Evidence
Published Research
[1]
Khavinson VK et al. Peptide Epitalon activates chromatin at the old age. Neuro Endocrinol Lett 2003;24:329-333 — PubMed 14647007
[2]
Anisimov VN et al. Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence. Biogerontology 2003;4:193-202 — PubMed 14501183
Research Use Only. All products sold by Lumen Peppers are intended solely for in vitro research and laboratory purposes. They are not drugs, supplements, or foods. Nothing on this page constitutes medical advice. Researchers are responsible for compliance with all applicable regulations. Last updated: April 14, 2026.