Peptide Handbook
Growth Hormone Peptides

GHRP-2

Growth Hormone Releasing Hexapeptide

Updated April 14, 2026

What is GHRP-2?

The most potent synthetic hexapeptide growth hormone secretagogue, producing the highest peak GH concentrations of any GHRP at equivalent doses. GHRP-2 activates the ghrelin receptor (GHS-R1a) with greater efficacy than GHRP-6, Hexarelin, or Ipamorelin while producing moderate cortisol and prolactin elevation — intermediate between the non-selective GHRP-6 and the highly selective Ipamorelin.

Research Profile

Structure 6 amino acids (~817 Da) — D-Ala-D-βNal-Ala-Trp-D-Phe-Lys-NH₂
Targets GHS-R1a (ghrelin receptor) — high potency
Research Focus Maximum GH secretion studies, dose-response pharmacology, GHRP potency comparison
Reconstitution Bacteriostatic water — 2 mg/mL
Stability 21 days at 2–8°C
Key distinction: Highest peak GH output of any GHRP — the gold standard for maximum acute GH release studies, with intermediate selectivity between GHRP-6 and Ipamorelin.

Published Research

[1] Bowers CY. Growth hormone-releasing peptide (GHRP). Cell Mol Life Sci 1998;54:1316-1329 — PubMed 9893709
[2] Laferrère B et al. Growth hormone releasing peptide-2 (GHRP-2) repeatedly stimulates GH secretion in humans. J Clin Endocrinol Metab 2005;90:6714-6720 — PubMed 16159940
Research Use Only. All products sold by Lumen Peppers are intended solely for in vitro research and laboratory purposes. They are not drugs, supplements, or foods. Nothing on this page constitutes medical advice. Researchers are responsible for compliance with all applicable regulations. Last updated: April 14, 2026.

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