A synthetic hexapeptide that potently stimulates growth hormone release through ghrelin receptor (GHS-R1a) activation. GHRP-6 was among the earliest GH secretagogues studied and produces the strongest hunger response of any GHRP — substantially increasing ghrelin and cortisol alongside GH. This non-selective profile makes it the preferred tool for studying the full spectrum of ghrelin receptor biology including orexigenic signaling.
Research FocusGH secretion, ghrelin biology, appetite stimulation, gastric motility
ReconstitutionBacteriostatic water — 2 mg/mL
Stability21 days at 2–8°C
Key distinction: Strongest appetite-stimulating GHRP — the pronounced hunger and cortisol response makes it the reference compound for full-spectrum ghrelin receptor biology, contrasting with Ipamorelin's selectivity.
Scientific Evidence
Published Research
[1]
Bowers CY et al. On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology 1984;114:1537-1545 — PubMed 6423384
[2]
Arvat E et al. Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS). Eur J Endocrinol 2001;144:R1-R5 — PubMed 11174825
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