A synthetic 16-amino-acid peptide representing a modified fragment of the C-terminal region (amino acids 176–191) of human growth hormone. Developed at Monash University, AOD-9604 isolates the lipolytic activity of full-length hGH while lacking effects on blood glucose, insulin sensitivity, or IGF-1 levels. Activates beta-3 adrenergic receptors on adipocytes, triggering hormone-sensitive lipase (HSL) cascade.
Research FocusAdipocyte lipolysis, lipogenesis inhibition, body composition
ReconstitutionBacteriostatic water — 1 mg/mL
Stability28 days at 2–8°C
Key distinction: Isolates the fat-metabolism fragment of growth hormone without affecting glucose, insulin, or IGF-1 — enabling focused lipolysis research without full GH confounders.
Scientific Evidence
Published Research
[1]
Ng FM et al. Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone. Horm Res 2000;53:274-278 — PubMed 11146367
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